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2022 Good Quality Sodium Thioglycolate - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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2022 Good Quality Sodium Thioglycolate - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name  Atosiban
CAS number  90779-69-4
Molecular formula  C43H67N11O12S2
Molecular weight  994.19
EINECS Number  806-815-5
Boiling point  1469.0±65.0 °C (Predicted)
Density  1.254±0.06 g/cm3(Predicted)
Storage conditions  -20°C
Solubility  H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


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2022 Good Quality Sodium Thioglycolate - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures

2022 Good Quality Sodium Thioglycolate - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures


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To be able to ideal satisfy client's requirements, all of our operations are strictly performed in line with our motto "High High-quality, Competitive Price tag, Fast Service" for 2022 Good Quality Sodium Thioglycolate - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Marseille, Washington, Serbia, We warmly welcome you to come to visit us personally. We hope to establish a long-term friendship based on equality and mutual benefit. If you want to get in touch with us, please do not hesitate to call. We will be your best choice.
  • The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
    5 Stars By Adelaide from Hungary - 2017.06.16 18:23
    Production management mechanism is completed, quality is guaranteed, high credibility and service let the cooperation is easy, perfect!
    5 Stars By Meredith from Algeria - 2018.12.14 15:26
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