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China Supplier Cas 16056-11-4 - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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China Supplier Cas 16056-11-4 - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name  Atosiban
CAS number  90779-69-4
Molecular formula  C43H67N11O12S2
Molecular weight  994.19
EINECS Number  806-815-5
Boiling point  1469.0±65.0 °C (Predicted)
Density  1.254±0.06 g/cm3(Predicted)
Storage conditions  -20°C
Solubility  H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


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China Supplier Cas 16056-11-4 - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures

China Supplier Cas 16056-11-4 - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures


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All we do is usually affiliated with our tenet " Buyer to start with, Belief to start with, devoting about the food packaging and environmental defense for China Supplier Cas 16056-11-4 - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Moldova, Colombia, Curacao, For more than ten years experience in this filed, our company has gained high reputation from home and abroad. So we welcome friends from all over the world to come and contact us, not only for business, but also for friendship.
  • Timely delivery, strict implementation of the contract provisions of the goods, encountered special circumstances, but also actively cooperate, a trustworthy company!
    5 Stars By Agatha from Pakistan - 2017.05.02 18:28
    The factory has advanced equipment, experienced staffs and good management level, so product quality had assurance, this cooperation is very relaxed and happy!
    5 Stars By Maggie from Accra - 2017.11.12 12:31
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