Excellent quality Disodium,4-Formylbenzene-1,3-Disulfonate - Human Growth Hormone for Children and Body Building – Gentolex
Excellent quality Disodium,4-Formylbenzene-1,3-Disulfonate - Human Growth Hormone for Children and Body Building – Gentolex Detail:
Product Detail
| CAS | 204656-20-2 | Molecular Formula | C172H265N43O51 |
| Molecular Weight | 3751.20 | Appearance | White |
| Storage Condition | Light resistance, 2-8 degree | Package | Aluminum foil bag/vial |
| Purity | ≥98% | Transportation | Cold Chain and cool storage delivery |
Ingredients of Liraglutide
Application
Type 2 diabetes
Liraglutide improves control of blood glucose. It reduces meal-related hyperglycemia (for 24 hours after administration) by increasing insulin secretion (only) when required by increasing glucose levels, delaying gastric emptying, and suppressing prandial glucagon secretion.
It is suitable for patients whose blood sugar is still poorly controlled after the maximum tolerated dose of metformin or sulfonylureas alone. It is used in combination with metformin or sulfonylureas.
It acts in a glucose-dependent manner, meaning it will stimulate insulin secretion only when blood glucose levels are higher than normal, preventing “overshoot”. Consequently, it shows negligible risk of hypoglycemia.
It has the potential for inhibiting apoptosis and stimulating regeneration of beta cells (seen in animal studies).
It decreases appetite and inhibits body weight gain, as shown in a head-to-head study versus glimepiride.
Pharmacological Action
Liraglutide is a GLP-1 analog with 97% sequence homology to human GLP-1, which can bind to and activate the GLP-1 receptor. The GLP-1 receptor is the target of native GLP-1, an endogenous incretin hormone that promotes glucose concentration-dependent insulin secretion from pancreatic β cells. Unlike native GLP-1, the pharmacokinetic and pharmacodynamic profiles of liraglutide in humans are suitable for a once-daily dosing regimen. After subcutaneous injection, its mechanism of prolonged action includes: self-association that slows absorption; binding to albumin; Higher enzyme stability and thus longer plasma half-life.
The activity of liraglutide is mediated by its specific interaction with the GLP-1 receptor, resulting in an increase in cyclic adenosine monophosphate (cAMP). Liraglutide stimulates insulin secretion in a glucose concentration-dependent manner, while reducing excess glucagon secretion in a glucose concentration-dependent manner.
Therefore, when blood glucose rises, insulin secretion is stimulated, while glucagon secretion is inhibited. In contrast, liraglutide reduces insulin secretion during hypoglycemia without affecting glucagon secretion. The hypoglycemic mechanism of liraglutide also includes a slight prolongation of gastric emptying time. Liraglutide reduces body weight and body fat mass by reducing hunger and energy intake.
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Our business puts emphasis over the administration, the introduction of talented staff, plus the construction of team building, attempting hard to boost the standard and liability consciousness of personnel customers. Our corporation successfully attained IS9001 Certification and European CE Certification of Excellent quality Disodium,4-Formylbenzene-1,3-Disulfonate - Human Growth Hormone for Children and Body Building – Gentolex , The product will supply to all over the world, such as: Southampton, Rio de Janeiro, Accra, Now, with the development of internet, and the trend of internationalization, we have decided to extend business to overseas market. With the propose of bringing more profits to oversea customers by providing directly abroad. So we have changed our mind, from home to abroad, hope to give our customers more profit, and looking forward to more chance to make business.
By Murray from Sacramento - 2017.07.07 13:00
The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
By Emily from Brisbane - 2018.11.28 16:25
