Factory supplied Caspofungin Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
Factory supplied Caspofungin Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:
Product Detail
| Name | N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin |
| CAS number | 14636-12-5 |
| Molecular formula | C52H74N16O15S2 |
| Molecular weight | 1227.37 |
| EINECS Number | 238-680-8 |
| Boiling point | 1824.0±65.0 °C (Predicted) |
| Density | 1.46±0.1 g/cm3(Predicted) |
| Storage conditions | Keep in dark place, Inert atmosphere, Store in freezer, under -15°C. |
| Acidity coefficient | (pKa) 9.90±0.15 (Predicted) |
Synonyms
[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.
Description
Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.
The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.
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Our progress depends about the advanced products ,fantastic talents and continuously strengthened technology forces for Factory supplied Caspofungin Acetate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Provence, New Orleans, Jamaica, They are sturdy modeling and promoting effectively all over the world. Never ever disappearing major functions within a quick time, it's a have to in your case of fantastic good quality. Guided by the principle of Prudence, Efficiency, Union and Innovation. the corporation. ake an excellent efforts to expand its international trade, raise its organization. rofit and raise its export scale. We've been confident that we've been going to have a bright prospect and to be distributed all over the world in the years to come.
By Rita from Jamaica - 2017.04.28 15:45
High production efficiency and good product quality, fast delivery and completed after-sale protection, a right choice, a best choice.
By Lindsay from Bahrain - 2018.09.19 18:37
