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Factory wholesale Sulconazole Nitrate - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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Factory wholesale Sulconazole Nitrate - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name  Atosiban
CAS number  90779-69-4
Molecular formula  C43H67N11O12S2
Molecular weight  994.19
EINECS Number  806-815-5
Boiling point  1469.0±65.0 °C (Predicted)
Density  1.254±0.06 g/cm3(Predicted)
Storage conditions  -20°C
Solubility  H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


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Factory wholesale Sulconazole Nitrate - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures

Factory wholesale Sulconazole Nitrate - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures


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Sticking to the belief of "Creating products of high quality and making friends with people from all over the world", we always put the interest of customers in the first place for Factory wholesale Sulconazole Nitrate - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Greenland, Qatar, Dominica, To have much more enterprise. ompanions, we've got updated the item list and seek for optimistic co-operation. Our web-site shows the latest and complete information and facts about our goods list and company. For further acknowledge, our consultant service group in Bulgaria will reply to all of the inquiries and complications immediately. They're going to make their finest effort to meet buyers need. Also we support the delivery of absolutely free samples. Business visits to our business in Bulgaria and factory are generally welcome for a win-win negotiation. Hope to expertise a happy company co-operation perform with you.
  • Goods just received, we are very satisfied, a very good supplier, hope to make persistent efforts to do better.
    5 Stars By Maria from The Swiss - 2017.01.11 17:15
    This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
    5 Stars By olivier musset from Buenos Aires - 2018.08.12 12:27
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