• head_banner_01

High Quality for Acetyl Carnitine - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

By using a full scientific excellent administration method, great quality and fantastic religion, we get good reputation and occupied this discipline for 2-Furoic Acid, 2-Isonitrosoacetophenone, Desmopressin Acetate Uses, We sincerely welcome overseas consumers to consult for your long-term cooperation as well as the mutual advancement.We strongly think that we will do superior and far better.
High Quality for Acetyl Carnitine - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

Product Detail

Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.


Product detail pictures:

High Quality for Acetyl Carnitine - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

High Quality for Acetyl Carnitine - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

High Quality for Acetyl Carnitine - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures


Related Product Guide:

Our well-equipped facilities and exceptional good quality manage throughout all stages of production enables us to guarantee total shopper satisfaction for High Quality for Acetyl Carnitine - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Philippines, Victoria, European, Meanwhile, we're building up and consummating triangle market & strategic cooperation in order to achieve a multi-win trade supply chain to expand our market vertically and horizontally for a brighter prospects. development. Our philosophy is to create cost-effective products and solutions, promote perfect services, cooperate for long-term and mutual benefits, firm a in depth mode of excellent suppliers system and marketing agents, brand strategic cooperation sales system.
  • We always believe that the details decides the company's product quality, in this respect, the company conform our requirements and the goods are meet our expectations.
    5 Stars By Nina from Qatar - 2018.12.22 12:52
    Good quality and fast delivery, it's very nice. Some products have a little bit problem, but the supplier replaced timely, overall, we are satisfied.
    5 Stars By Sabrina from Cyprus - 2017.03.08 14:45
    Write your message here and send it to us