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Hot Sale for Oxytocin - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

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Our firm aims to operating faithfully, serving to all of our consumers , and working in new technology and new machine continually for 2-Isonitrosoacetophenone, Rhodium(Iii) Nitrate 10139-58-9, Dibenzosuberone, In order to expand our international market, we mainly supply our oversea customers Top quality performance products and service.
Hot Sale for Oxytocin - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

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Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.


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Hot Sale for Oxytocin - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Hot Sale for Oxytocin - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Hot Sale for Oxytocin - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures


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carry on to further improve, to guarantee merchandise high-quality in line with market and buyer standard necessities. Our organization has a top quality assurance procedure have already been established for Hot Sale for Oxytocin - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: French, Belgium, Mauritius, In order to meet our market demands, we have paied more attention to the quality of our products and services. Now we can meet customers' special requirements for special designs. We persistently develop our enterprise spirit "quality lives the enterprise, credit assures cooperation and keep the motto in our minds: customers first.
  • It is really lucky to meet such a good supplier, this is our most satisfied cooperation, I think we will work again!
    5 Stars By Delia from Namibia - 2018.06.21 17:11
    We have been appreciated the Chinese manufacturing, this time also did not let us disappoint,good job!
    5 Stars By Joanna from Spain - 2018.05.15 10:52
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