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Leading Manufacturer for Naturally Occurring Amino Acids - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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Leading Manufacturer for Naturally Occurring Amino Acids - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name  Atosiban
CAS number  90779-69-4
Molecular formula  C43H67N11O12S2
Molecular weight  994.19
EINECS Number  806-815-5
Boiling point  1469.0±65.0 °C (Predicted)
Density  1.254±0.06 g/cm3(Predicted)
Storage conditions  -20°C
Solubility  H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


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Leading Manufacturer for Naturally Occurring Amino Acids - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures

Leading Manufacturer for Naturally Occurring Amino Acids - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures


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"Sincerity, Innovation, Rigorousness, and Efficiency" is the persistent conception of our company for the long-term to develop together with customers for mutual reciprocity and mutual benefit for Leading Manufacturer for Naturally Occurring Amino Acids - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Serbia, Orlando, Austria, We are confident that we are able to provide you with opportunities and will be a valuable business partner of you. We look forward to working with you soon. Learn more about the types of products that we work with or contact us now directly with your inquiries. You are welcome to contact us anytime!
  • In China, we have purchased many times, this time is the most successful and most satisfactory, a sincere and realiable Chinese manufacturer!
    5 Stars By Bernice from Adelaide - 2017.09.29 11:19
    This supplier offers high quality but low price products, it is really a nice manufacturer and business partner.
    5 Stars By Grace from Morocco - 2018.12.11 14:13
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