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Low price for Tenofoviral Afenamide Fumarate - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex

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Low price for Tenofoviral Afenamide Fumarate - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex Detail:

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Name  Daptomycin
CAS number  103060-53-3
Molecular formula  C72H101N17O26
Molecular weight  1620.67
EINECS Number  600-389-2
Melting point  202-204°C
Boiling point  2078.2±65.0 °C (Predicted)
Density  1.45±0.1 g/cm3(Predicted)
Flash point  87℃
Storage conditions  Sealed in dry, Store in freezer, under -20°C
Solubility  Methanol:soluble5mg/mL
Acidity coefficient  (pKa) 4.00±0.10 (Predicted)
Form  powder
Color  colorless to faint yellow

Synonyms

N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-];N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone;DAPTOMYCINE;Dapcin;Daptomycin,>=99%;DaptomycinReadyMadeSolution;Daptomycin(LY146032)

Description

The antibiotic daptomycin is a cyclic lipopeptide antibiotic with a new structure extracted from the fermentation broth of Streptomyces (S. reseosporus), which hinders the biosynthesis of bacterial cell wall peptidoglycan by disturbing the transport of amino acids in the cell membrane. Altering the properties of the cytoplasmic membrane can disrupt bacterial membrane function in multiple ways and rapidly kill Gram-positive bacteria. In addition to its ability to act on most clinically relevant Gram-positive bacteria, daptomycin is more important for isolated strains that have shown resistance to methicillin, vancomycin, and linezolid in vitro. It has potent activity, and this property has very important clinical implications for critically ill infected patients. Eosinophilic pneumonia is a rare and very serious disease with symptoms including fever, cough, shortness of breath, and difficulty breathing.

Antibacterial Effect

Daptomycin has good bacteriostatic activity against various antibiotic-resistant bacteria, such as MIC=0.06-0.5 μg/ml for methicillin-resistant Staphylococcus aureus (MRSA), and methicillin-resistant Staphylococcus aureus (MRSA). MIC=0.0625~1μg/ml for bacteria, MIC=0.12~0.5μg/ml for oxacillin-resistant Staphylococcus epidermidis, MIC=2.5μg/ml for enterococcus highly resistant to aminoglycoside antibiotics, MIC=2.5μg/ml for GmrBIa -The MIC of Enterococcus is 0.5~1μg/ml, and the MIC of Enterococcus resistant to glycopeptide antibiotics is 1~2μg/ml.


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Low price for Tenofoviral Afenamide Fumarate - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

Low price for Tenofoviral Afenamide Fumarate - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

Low price for Tenofoviral Afenamide Fumarate - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures


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Our enterprise since its inception, usually regards product top quality as business life, repeatedly enhance manufacturing technology, make improvements to product excellent and continuously strengthen enterprise total high quality administration, in strict accordance with all the national standard ISO 9001:2000 for Low price for Tenofoviral Afenamide Fumarate - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex , The product will supply to all over the world, such as: Senegal, Sheffield, Vancouver, If any item be of interest to you, you should let us know. We will try our best to satisfy your requirements with high quality goods, the best prices and prompt delivery. You should feel free to contact us at any time. We will reply you when we receive your inquiries. Make sure you note that samples are available before we start our business.
  • The product classification is very detailed that can be very accurate to meet our demand, a professional wholesaler.
    5 Stars By Doreen from Slovak Republic - 2018.12.30 10:21
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