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OEM manufacturer Cas 2309-49-1 - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex

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OEM manufacturer Cas 2309-49-1 - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex Detail:

Product Detail

Name  Daptomycin
CAS number  103060-53-3
Molecular formula  C72H101N17O26
Molecular weight  1620.67
EINECS Number  600-389-2
Melting point  202-204°C
Boiling point  2078.2±65.0 °C (Predicted)
Density  1.45±0.1 g/cm3(Predicted)
Flash point  87℃
Storage conditions  Sealed in dry, Store in freezer, under -20°C
Solubility  Methanol:soluble5mg/mL
Acidity coefficient  (pKa) 4.00±0.10 (Predicted)
Form  powder
Color  colorless to faint yellow

Synonyms

N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-];N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone;DAPTOMYCINE;Dapcin;Daptomycin,>=99%;DaptomycinReadyMadeSolution;Daptomycin(LY146032)

Description

The antibiotic daptomycin is a cyclic lipopeptide antibiotic with a new structure extracted from the fermentation broth of Streptomyces (S. reseosporus), which hinders the biosynthesis of bacterial cell wall peptidoglycan by disturbing the transport of amino acids in the cell membrane. Altering the properties of the cytoplasmic membrane can disrupt bacterial membrane function in multiple ways and rapidly kill Gram-positive bacteria. In addition to its ability to act on most clinically relevant Gram-positive bacteria, daptomycin is more important for isolated strains that have shown resistance to methicillin, vancomycin, and linezolid in vitro. It has potent activity, and this property has very important clinical implications for critically ill infected patients. Eosinophilic pneumonia is a rare and very serious disease with symptoms including fever, cough, shortness of breath, and difficulty breathing.

Antibacterial Effect

Daptomycin has good bacteriostatic activity against various antibiotic-resistant bacteria, such as MIC=0.06-0.5 μg/ml for methicillin-resistant Staphylococcus aureus (MRSA), and methicillin-resistant Staphylococcus aureus (MRSA). MIC=0.0625~1μg/ml for bacteria, MIC=0.12~0.5μg/ml for oxacillin-resistant Staphylococcus epidermidis, MIC=2.5μg/ml for enterococcus highly resistant to aminoglycoside antibiotics, MIC=2.5μg/ml for GmrBIa -The MIC of Enterococcus is 0.5~1μg/ml, and the MIC of Enterococcus resistant to glycopeptide antibiotics is 1~2μg/ml.


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OEM manufacturer Cas 2309-49-1 - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

OEM manufacturer Cas 2309-49-1 - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

OEM manufacturer Cas 2309-49-1 - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures


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We thinks what clients think, the urgency of urgency to act from the interests of a client position of theory, allowing for greater quality, lessen processing costs, price ranges are much more reasonable, won the new and outdated shoppers the support and affirmation for OEM manufacturer Cas 2309-49-1 - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex , The product will supply to all over the world, such as: Curacao, Swaziland, Hamburg, Ensuring high product quality by choosing the best suppliers, now we have also implemented complete quality control processes throughout our sourcing procedures. Meanwhile, our access to a large range of factories, coupled with our excellent management, also ensures that we can quickly fill your requirements at the best prices, regardless the order size.
  • The quality of the products is very good, especially in the details, can be seen that the company work actively to satisfy customer's interest, a nice supplier.
    5 Stars By Hilary from Jordan - 2018.09.21 11:44
    Superb technology, perfect after-sales service and efficient work efficiency, we think this is our best choice.
    5 Stars By Catherine from Finland - 2017.05.31 13:26
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