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OEM/ODM Manufacturer Thioglycolate De Sodium - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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We offer great strength in quality and development,merchandising,sales and marketing and operation for Mercury 2 Acetate, Cypionate, Sunitinib Malate Intermediate, Our customers mainly distributed in the North America, Africa and Eastern Europe. we will source top quality goods using the really aggressive selling price.
OEM/ODM Manufacturer Thioglycolate De Sodium - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name  Atosiban
CAS number  90779-69-4
Molecular formula  C43H67N11O12S2
Molecular weight  994.19
EINECS Number  806-815-5
Boiling point  1469.0±65.0 °C (Predicted)
Density  1.254±0.06 g/cm3(Predicted)
Storage conditions  -20°C
Solubility  H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


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OEM/ODM Manufacturer Thioglycolate De Sodium - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures

OEM/ODM Manufacturer Thioglycolate De Sodium - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures


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  • With a positive attitude of "regard the market, regard the custom, regard the science", the company works actively to do research and development. Hope we have a future business relationships and achieving mutual success.
    5 Stars By Marcie Green from Barcelona - 2018.10.09 19:07
    The goods are very perfect and the company sales manager is warmful, we will come to this company to purchase next time.
    5 Stars By Doreen from Israel - 2017.09.28 18:29
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