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OEM/ODM Supplier Bromoethylamine Hydrobromide - Atosiban Acetate Used for Anti Premature Birth – Gentolex

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OEM/ODM Supplier Bromoethylamine Hydrobromide - Atosiban Acetate Used for Anti Premature Birth – Gentolex Detail:

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Name  Atosiban
CAS number  90779-69-4
Molecular formula  C43H67N11O12S2
Molecular weight  994.19
EINECS Number  806-815-5
Boiling point  1469.0±65.0 °C (Predicted)
Density  1.254±0.06 g/cm3(Predicted)
Storage conditions  -20°C
Solubility  H2O:≤100 mg/mL

Description

Atosiban acetate is a disulfide-bonded cyclic polypeptide consisting of 9 amino acids. It is a modified oxytocin molecule at positions 1, 2, 4 and 8. The N-terminus of the peptide is 3-mercaptopropionic acid (thiol and The sulfhydryl group of [Cys]6 forms a disulfide bond), the C-terminal is in the form of an amide, the second amino acid at the N-terminal is an ethylated modified [D-Tyr(Et)]2, and atosiban acetate is used in medicines as vinegar It exists in the form of an acid salt, commonly known as atosiban acetate.

Application

Atosiban is an oxytocin and vasopressin V1A combined receptor antagonist, the oxytocin receptor is structurally similar to the vasopressin V1A receptor. When the oxytocin receptor is blocked, oxytocin can still act through the V1A receptor, so it is necessary to block the above two receptor pathways at the same time, and a single antagonism of one receptor can effectively inhibit uterine contraction. This is also one of the main reasons why β-receptor agonists, calcium channel blockers and prostaglandin synthase inhibitors cannot effectively inhibit uterine contractions.

Effect

Atosiban is a combined receptor antagonist of oxytocin and vasopressin V1A, its chemical structure is similar to the two, and it has a high affinity for receptors, and competes with oxytocin and vasopressin V1A receptors, thereby blocking the action pathway of oxytocin and vasopressin and reducing uterine contractions.


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OEM/ODM Supplier Bromoethylamine Hydrobromide - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures

OEM/ODM Supplier Bromoethylamine Hydrobromide - Atosiban Acetate Used for Anti Premature Birth – Gentolex detail pictures


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Our concentrate on is always to consolidate and enhance the excellent and service of present solutions, in the meantime regularly develop new products to meet distinctive customers' demands for OEM/ODM Supplier Bromoethylamine Hydrobromide - Atosiban Acetate Used for Anti Premature Birth – Gentolex , The product will supply to all over the world, such as: Mozambique, Estonia, Mexico, To win customers' confidence, Best Source has set up a strong sales and after-sales team to deliver the best product and service. Best Source abides by the idea of "Grow with customer" and philosophy of "Customer-oriented" to achieve cooperation of mutual trust and benefit. Best Source will always stand ready to cooperate with you. Let's grow together!
  • This supplier stick to the principle of "Quality first, Honesty as base", it is absolutely to be trust.
    5 Stars By Rachel from Israel - 2018.06.21 17:11
    This is the first business after our company establish, products and services are very satisfying, we have a good start, we hope to cooperate continuous in the future!
    5 Stars By May from Montreal - 2018.02.21 12:14
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