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OEM/ODM Supplier Bromoethylamine Hydrobromide - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex

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OEM/ODM Supplier Bromoethylamine Hydrobromide - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex Detail:

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Name  Daptomycin
CAS number  103060-53-3
Molecular formula  C72H101N17O26
Molecular weight  1620.67
EINECS Number  600-389-2
Melting point  202-204°C
Boiling point  2078.2±65.0 °C (Predicted)
Density  1.45±0.1 g/cm3(Predicted)
Flash point  87℃
Storage conditions  Sealed in dry, Store in freezer, under -20°C
Solubility  Methanol:soluble5mg/mL
Acidity coefficient  (pKa) 4.00±0.10 (Predicted)
Form  powder
Color  colorless to faint yellow

Synonyms

N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-];N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone;DAPTOMYCINE;Dapcin;Daptomycin,>=99%;DaptomycinReadyMadeSolution;Daptomycin(LY146032)

Description

The antibiotic daptomycin is a cyclic lipopeptide antibiotic with a new structure extracted from the fermentation broth of Streptomyces (S. reseosporus), which hinders the biosynthesis of bacterial cell wall peptidoglycan by disturbing the transport of amino acids in the cell membrane. Altering the properties of the cytoplasmic membrane can disrupt bacterial membrane function in multiple ways and rapidly kill Gram-positive bacteria. In addition to its ability to act on most clinically relevant Gram-positive bacteria, daptomycin is more important for isolated strains that have shown resistance to methicillin, vancomycin, and linezolid in vitro. It has potent activity, and this property has very important clinical implications for critically ill infected patients. Eosinophilic pneumonia is a rare and very serious disease with symptoms including fever, cough, shortness of breath, and difficulty breathing.

Antibacterial Effect

Daptomycin has good bacteriostatic activity against various antibiotic-resistant bacteria, such as MIC=0.06-0.5 μg/ml for methicillin-resistant Staphylococcus aureus (MRSA), and methicillin-resistant Staphylococcus aureus (MRSA). MIC=0.0625~1μg/ml for bacteria, MIC=0.12~0.5μg/ml for oxacillin-resistant Staphylococcus epidermidis, MIC=2.5μg/ml for enterococcus highly resistant to aminoglycoside antibiotics, MIC=2.5μg/ml for GmrBIa -The MIC of Enterococcus is 0.5~1μg/ml, and the MIC of Enterococcus resistant to glycopeptide antibiotics is 1~2μg/ml.


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OEM/ODM Supplier Bromoethylamine Hydrobromide - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

OEM/ODM Supplier Bromoethylamine Hydrobromide - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

OEM/ODM Supplier Bromoethylamine Hydrobromide - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures


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Persisting in "High top quality, Prompt Delivery, Aggressive Price", now we have established long-term cooperation with customers from the two overseas and domestically and get new and aged clients' large comments for OEM/ODM Supplier Bromoethylamine Hydrobromide - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex , The product will supply to all over the world, such as: Lithuania, Juventus, Latvia, Now, we are trying to enter new markets where we do not have a presence and developing the markets we have now the already penetrated. On account of superior quality and competitive price , we'll be the market leader, be sure to don??¥t hesitate to contact us by phone or email, if you are interested in any of our solutions.
  • This supplier's raw material quality is stable and reliable, has always been in accordance with the requirements of our company to provide the goods that quality meet our requirements.
    5 Stars By Caroline from Argentina - 2018.06.05 13:10
    With a positive attitude of "regard the market, regard the custom, regard the science", the company works actively to do research and development. Hope we have a future business relationships and achieving mutual success.
    5 Stars By Ivan from Irish - 2017.06.22 12:49
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