• head_banner_01

Reasonable price Amino Acids In Rice - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

To continually enhance the management technique by virtue of your rule of "sincerely, great faith and high-quality are the base of company development", we widely absorb the essence of similar merchandise internationally, and continuously build new merchandise to meet the demands of customers for Lead 4 Acetate, Lithium And Bromide, 25 Sorafenib, Wanting on the long run, a protracted way to go, continually striving to become the all team with full enthusiasm, one hundred times the confidence and put our company created a beautiful environment, advanced merchandise, good quality first-class modern business and get the job done hard!
Reasonable price Amino Acids In Rice - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex Detail:

Product Detail

Name  Leuprorelin
CAS number  53714-56-0
Molecular formula  C59H84N16O12
Molecular weight  1209.4
EINECS Number  633-395-9
Specific rotation  D25 -31.7° (c = 1 in 1% acetic acid)
Density  1.44±0.1 g/cm3(Predicted)
Storage condition  -15°C
Form  Neat
Acidity coefficient  (pKa) 9.82±0.15 (Predicted)
Water solubility  Soluble in water at 1mg/ml

Synonyms

LH-RHLEUPROLIDE;LEUPROLIDE;LEUPROLIDE(HUMAN);LEUPRORELIN;[DES-GLY10,D-LEU6,PRO-NHET9]-LUTEINIZINGHORMONE-RELEASINGHORMONEHUMAN;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGHORMONE;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGFACTOR;[DES-GLY10,D-LEU6,PRO-NHET9]-LH-RH(HUMAN)

Pharmacological Effect

Leuprolide, goserelin, triprelin, and nafarelin are several drugs commonly used in clinical practice to remove ovaries for the treatment of premenopausal breast cancer and prostate cancer. (referred to as GnRH-a drugs), GnRH-a drugs are similar in structure to GnRH and compete with pituitary GnRH receptors. That is, the gonadotropin secreted by the pituitary decreases, which leads to a significant decrease in the sex hormone secreted by the ovary.

Leuprolide is a gonadotropin-releasing hormone (GnRH) analog, a peptide composed of 9 amino acids. This product can effectively inhibit the function of the pituitary-gonadal system, the resistance to proteolytic enzymes and the affinity to the pituitary GnRH receptor are stronger than GnRH, and the activity of promoting the release of luteinizing hormone (LH) is about 20 times that of GnRH. It also has a stronger inhibitory effect on pituitary-gonad function than GnRH. In the initial stage of treatment, follicle stimulating hormone (FSH), LH, estrogen or androgen may be temporarily increased, and then, due to the decreased responsiveness of the pituitary gland, the secretion of FSH, LH and estrogen or androgen is inhibited, resulting in dependence on sex hormones. Sexual diseases (such as prostate cancer, endometriosis, etc.) have a therapeutic effect.

At present, the acetate salt of leuprolide is mainly used clinically, because the performance of leuprolide acetate is more stable at room temperature. Liquid should be discarded. It can be used for the drug castration treatment of endometriosis and uterine fibroids, central precocious puberty, premenopausal breast cancer and prostate cancer, and also for functional uterine bleeding that is contraindicated or ineffective for conventional hormone therapy. It can also be used as a premedication before endometrial resection, which can evenly thin the endometrium, reduce edema, and reduce the difficulty of surgery.


Product detail pictures:

Reasonable price Amino Acids In Rice - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex detail pictures

Reasonable price Amino Acids In Rice - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex detail pictures


Related Product Guide:

We've been committed to offering easy,time-saving and money-saving one-stop purchasing service of consumer for Reasonable price Amino Acids In Rice - Paclitaxel 33069-62-4 Anti-tumor Botanical Medicine for Ovarian Cancer, Breast Cancer – Gentolex , The product will supply to all over the world, such as: Johor, Albania, Manila, We will do our utmost to cooperate & satisfied with you relying on top-grade quality and competitive price and best after service ,sincerely look forward to cooperating with you and make achievements in the future!
  • We have been cooperated with this company for many years, the company always ensure timely delivery ,good quality and correct number, we are good partners.
    5 Stars By Isabel from Dominica - 2017.09.30 16:36
    On this website, product categories is clear and rich, I can find the product I want very quickly and easily, this is really very good!
    5 Stars By Honey from Houston - 2018.09.29 13:24
    Write your message here and send it to us