• head_banner_01

Reasonable price Trisodium Methanetrisulfonate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

abide by the contract", conforms to the market requirement, joins in the market competition by its high quality as well as provides more comprehensive and excellent service for clients to let them become big winner. The pursue of the company, is the clients' satisfaction for M1 Pseudouridine, Dioctyl Sebacate_Dos 122-62-3, Organic Intermediate, We fully welcome customers from all over the world to establish stable and mutually beneficial business relationships, to have a bright future together.
Reasonable price Trisodium Methanetrisulfonate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

Product Detail

Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.


Product detail pictures:

Reasonable price Trisodium Methanetrisulfonate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Reasonable price Trisodium Methanetrisulfonate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Reasonable price Trisodium Methanetrisulfonate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures


Related Product Guide:

We take pleasure in a really excellent name amongst our shoppers for our exceptional product or service excellent, competitive rate and also the greatest services for Reasonable price Trisodium Methanetrisulfonate - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Adelaide, Saudi Arabia, Singapore, We have top engineers in these industries and an efficient team in the research. What is more, now we have our own archives mouths and markets in China at low cost. Therefore, we can meet different inquiries from different clients. Remember to find our website to check more information from our merchandise.
  • As a veteran of this industry, we can say that the company can be a leader in the industry, select them is right.
    5 Stars By Judy from Juventus - 2017.05.02 18:28
    We have been appreciated the Chinese manufacturing, this time also did not let us disappoint,good job!
    5 Stars By Amelia from Swansea - 2017.12.31 14:53
    Write your message here and send it to us