English
  • head_banner_01
Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Featured Image
  • Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex
  • Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

The client satisfaction is our primary concentrate on. We uphold a consistent level of professionalism, top quality, credibility and service for Lithium Bromide 7550-35-8, 3-Amino-1-Propanesulfonic Acid, China Manufacturer Organic Intermediate Cas: 1739-84-0 1, We welcome you to visit our factory and look forward to establishing friendly business relationships with customers at home and abroad in the near future.
Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex Detail:

Product Detail

Name  N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
CAS number  14636-12-5
Molecular formula  C52H74N16O15S2
Molecular weight  1227.37
EINECS Number  238-680-8
Boiling point  1824.0±65.0 °C (Predicted)
Density  1.46±0.1 g/cm3(Predicted)
Storage conditions  Keep in dark place, Inert atmosphere, Store in freezer, under -15°C.
Acidity coefficient  (pKa) 9.90±0.15 (Predicted)

Synonyms

[N-α-Triglycyl-8-lysine]-vasopressin;130:PN: WO2010033207SEQID:171claiMedprotein; 1-Triglycyl-8-lysineVasopressin; Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin; Nα-Glycyl-glycyl-glycyl-lysine-vasopressin; Nα-Glycylglycylglycyl-vasopressin; Nα-Gly-Gly-Gly-8-Lys-vasopressin; Terlipressin, Terlipressine, Terlipressina, Terlipressinum.

Description

Terlipressin, whose chemical name is triglycyllysine vasopressin, is a new synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. It is acted by aminopeptidase in vivo to slowly “release” the active lysine vasopressin after removing the three glycyl residues at its N-terminus. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

The pharmacological effect of terlipressin is to contract splanchnic vascular smooth muscle and reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow and portal pressure. On the other hand, it can also reduce plasma The effect of renin concentration, thereby increasing renal blood flow, improving renal function and increasing urine output in patients with hepatorenal syndrome. Terlipressin is currently the only drug that can improve the survival rate of patients with esophageal variceal hemorrhage. It was mainly used in the clinical treatment of variceal hemorrhage. In addition, terlipressin has also been successfully used in the liver and kidney. In general, it is likely to play a beneficial role in coexisting refractory shock and cardiopulmonary resuscitation. Compared with vasopressin, it has a long-lasting effect, does not cause dangerous complications, including fibrinolysis and serious complications in the cardiovascular system, and is simple to use (intravenous injection), which is more suitable for acute and critical care. Rescue and treatment of critically ill patients.

Product detail pictures:

Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex detail pictures

Related Product Guide:
Assume full accountability to fulfill all demands of our purchasers; attain continual advancements by marketing the advancement of our clientele; grow to be the final permanent cooperative partner of purchasers and maximize the interests of purchasers for Reliable Supplier 2-(4-Hydroxy-6-Methylnicotinamido)-2-(4-Hydroxyphenyl)Acetic Acid - Terlipressin Acetate for Esophageal Variceal Bleeding – Gentolex , The product will supply to all over the world, such as: Slovakia, Moldova, Mauritius, Insisting on the high quality generation line management and customers expert assistance, we now have designed our resolution to supply our buyers using the to start with amount getting and just after services practical experience. Maintaining the prevailing friendly relations with our buyers, we however innovate our solution lists all of the time to satisfy the brand new demands and adhere to the most up-to-date development of the market in Malta. We have been ready to face the worries and make the improve to understand all the possibilities in international trade.
    • The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.
    5 Stars By Chris Fountas from Juventus - 2018.09.21 11:01
    Sales manager is very enthusiastic and professional, gave us a great concessions and product quality is very good,thank you very much!
    5 Stars By Kevin Ellyson from Haiti - 2017.02.14 13:19
    Write your message here and send it to us

    Related PRODUCTS

    Hit enter to search or ESC to close