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Top Quality Acetate De Zinc - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex

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Top Quality Acetate De Zinc - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex Detail:

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Name  Daptomycin
CAS number  103060-53-3
Molecular formula  C72H101N17O26
Molecular weight  1620.67
EINECS Number  600-389-2
Melting point  202-204°C
Boiling point  2078.2±65.0 °C (Predicted)
Density  1.45±0.1 g/cm3(Predicted)
Flash point  87℃
Storage conditions  Sealed in dry, Store in freezer, under -20°C
Solubility  Methanol:soluble5mg/mL
Acidity coefficient  (pKa) 4.00±0.10 (Predicted)
Form  powder
Color  colorless to faint yellow

Synonyms

N-[N-(1-Oxodecyl)-L-Trp-D-Asn-L-Asp-]-cyclo[L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-4-(2-aminophenyl)-4-oxo-L-Abu-];N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-];N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone;DAPTOMYCINE;Dapcin;Daptomycin,>=99%;DaptomycinReadyMadeSolution;Daptomycin(LY146032)

Description

The antibiotic daptomycin is a cyclic lipopeptide antibiotic with a new structure extracted from the fermentation broth of Streptomyces (S. reseosporus), which hinders the biosynthesis of bacterial cell wall peptidoglycan by disturbing the transport of amino acids in the cell membrane. Altering the properties of the cytoplasmic membrane can disrupt bacterial membrane function in multiple ways and rapidly kill Gram-positive bacteria. In addition to its ability to act on most clinically relevant Gram-positive bacteria, daptomycin is more important for isolated strains that have shown resistance to methicillin, vancomycin, and linezolid in vitro. It has potent activity, and this property has very important clinical implications for critically ill infected patients. Eosinophilic pneumonia is a rare and very serious disease with symptoms including fever, cough, shortness of breath, and difficulty breathing.

Antibacterial Effect

Daptomycin has good bacteriostatic activity against various antibiotic-resistant bacteria, such as MIC=0.06-0.5 μg/ml for methicillin-resistant Staphylococcus aureus (MRSA), and methicillin-resistant Staphylococcus aureus (MRSA). MIC=0.0625~1μg/ml for bacteria, MIC=0.12~0.5μg/ml for oxacillin-resistant Staphylococcus epidermidis, MIC=2.5μg/ml for enterococcus highly resistant to aminoglycoside antibiotics, MIC=2.5μg/ml for GmrBIa -The MIC of Enterococcus is 0.5~1μg/ml, and the MIC of Enterococcus resistant to glycopeptide antibiotics is 1~2μg/ml.


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Top Quality Acetate De Zinc - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

Top Quality Acetate De Zinc - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures

Top Quality Acetate De Zinc - Daptomycin 103060-53-3 for Infectious Diseases  – Gentolex detail pictures


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"Quality 1st, Honesty as base, Sincere company and mutual profit" is our idea, in an effort to create consistently and pursue the excellence for Top Quality Acetate De Zinc - Daptomycin 103060-53-3 for Infectious Diseases – Gentolex , The product will supply to all over the world, such as: Turkey, Japan, Brisbane, Now, we professionally supplies customers with our main products And our business is not only the "buy" and "sell", but also focus on more. We target to be your loyal supplier and long-term cooperator in China. Now, We hope to be the friends with you.
  • Customer service staff and sales man are very patience and they all good at English, product's arrival is also very timely, a good supplier.
    5 Stars By Odelette from Mexico - 2017.09.26 12:12
    Adhering to the business principle of mutual benefits, we have a happy and successful transaction, we think we will be the best business partner.
    5 Stars By Barbara from Switzerland - 2018.11.28 16:25
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