• head_banner_01

Wholesale Discount Low Sodium And Chloride - Liraglutide Anti-Diabetics for Blood Sugar Control CAS NO.204656-20-2 – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

Reliable good quality and very good credit standing are our principles, which will help us at a top-ranking position. Adhering to your tenet of "quality 1st, purchaser supreme" for Voriconazole, 1-Ethoxycarbonyl-4-Piperidinone, Benzalkonium Chloride Cold Sore, Our firm warmly welcome friends from everywhere in the globe to visit, examine and negotiate business enterprise.
Wholesale Discount Low Sodium And Chloride - Liraglutide Anti-Diabetics for Blood Sugar Control CAS NO.204656-20-2 – Gentolex Detail:

Product Detail

CAS 204656-20-2 Molecular Formula C172H265N43O51  
Molecular Weight 3751.20 Appearance White
Storage Condition Light resistance, 2-8 degree Package Aluminum foil bag/vial
Purity ≥98% Transportation Cold Chain and cool storage delivery

Ingredients of Liraglutide

Application

Type 2 diabetes

Liraglutide improves control of blood glucose. It reduces meal-related hyperglycemia (for 24 hours after administration) by increasing insulin secretion (only) when required by increasing glucose levels, delaying gastric emptying, and suppressing prandial glucagon secretion.
It is suitable for patients whose blood sugar is still poorly controlled after the maximum tolerated dose of metformin or sulfonylureas alone. It is used in combination with metformin or sulfonylureas.
It acts in a glucose-dependent manner, meaning it will stimulate insulin secretion only when blood glucose levels are higher than normal, preventing “overshoot”. Consequently, it shows negligible risk of hypoglycemia.
It has the potential for inhibiting apoptosis and stimulating regeneration of beta cells (seen in animal studies).
It decreases appetite and inhibits body weight gain, as shown in a head-to-head study versus glimepiride.

Pharmacological Action

Liraglutide is a GLP-1 analog with 97% sequence homology to human GLP-1, which can bind to and activate the GLP-1 receptor. The GLP-1 receptor is the target of native GLP-1, an endogenous incretin hormone that promotes glucose concentration-dependent insulin secretion from pancreatic β cells. Unlike native GLP-1, the pharmacokinetic and pharmacodynamic profiles of liraglutide in humans are suitable for a once-daily dosing regimen. After subcutaneous injection, its mechanism of prolonged action includes: self-association that slows absorption; binding to albumin; Higher enzyme stability and thus longer plasma half-life.

The activity of liraglutide is mediated by its specific interaction with the GLP-1 receptor, resulting in an increase in cyclic adenosine monophosphate (cAMP). Liraglutide stimulates insulin secretion in a glucose concentration-dependent manner, while reducing excess glucagon secretion in a glucose concentration-dependent manner.

Therefore, when blood glucose rises, insulin secretion is stimulated, while glucagon secretion is inhibited. In contrast, liraglutide reduces insulin secretion during hypoglycemia without affecting glucagon secretion. The hypoglycemic mechanism of liraglutide also includes a slight prolongation of gastric emptying time. Liraglutide reduces body weight and body fat mass by reducing hunger and energy intake.


Product detail pictures:

Wholesale Discount Low Sodium And Chloride - Liraglutide Anti-Diabetics for Blood Sugar Control CAS NO.204656-20-2 – Gentolex detail pictures


Related Product Guide:

To meet the customers' over-expected satisfaction , we have our strong team to provide our best overall service which includes marketing, sales, designing, production, quality controlling, packing, warehousing and logistics for Wholesale Discount Low Sodium And Chloride - Liraglutide Anti-Diabetics for Blood Sugar Control CAS NO.204656-20-2 – Gentolex , The product will supply to all over the world, such as: Turkey, Salt Lake City, Georgia, What is good price? We provide customers with factory price. In the premise of good quality, efficiency will have to be paid attention to and maintain appropriate low and healthy profits. What is a fast delivery? We make the delivery according to customers' requirements. Although delivery time depends on the order quantity and the complexity of it, we still try to supply products and solutions in time. Sincerely hope we could have long term business relationship.
  • This manufacturers not only respected our choice and requirements, but also gave us a lot of good suggestions, ultimately, we successfully completed the procurement tasks.
    5 Stars By Sabina from Sevilla - 2018.10.01 14:14
    We have been engaged in this industry for many years, we appreciate the work attitude and production capacity of the company, this is a reputable and professional manufacturer.
    5 Stars By Rita from Sheffield - 2017.07.07 13:00
    Write your message here and send it to us