• head_banner_01

Wholesale Vancomycin And Tobramycin - Leuprorelin Acetate Regulates Secretion of Gonadal Hormones – Gentolex

Short Description:


Product Detail

Product Tags

Related Video

Feedback (2)

Adhering to your principle of "quality, assistance, performance and growth", we have now gained trusts and praises from domestic and international customer for 3-Amino-1-Propanesulfonic Acid, 2-Amino-2-Methylpropanenitrile Hydrochloride, 10 Mm Ammonium Acetate, Our intention is to assist clients understand their ambitions. We are earning wonderful attempts to realize this win-win predicament and sincerely welcome you to be a part of us.
Wholesale Vancomycin And Tobramycin - Leuprorelin Acetate Regulates Secretion of Gonadal Hormones – Gentolex Detail:

Product Detail

Name  Leuprorelin
CAS number  53714-56-0
Molecular formula  C59H84N16O12
Molecular weight  1209.4
EINECS Number  633-395-9
Specific rotation  D25 -31.7° (c = 1 in 1% acetic acid)
Density  1.44±0.1 g/cm3(Predicted)
Storage condition  -15°C
Form  Neat
Acidity coefficient  (pKa) 9.82±0.15 (Predicted)
Water solubility  Soluble in water at 1mg/ml

Synonyms

LH-RHLEUPROLIDE;LEUPROLIDE;LEUPROLIDE(HUMAN);LEUPRORELIN;[DES-GLY10,D-LEU6,PRO-NHET9]-LUTEINIZINGHORMONE-RELEASINGHORMONEHUMAN;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGHORMONE;(DES-GLY10,D-LEU6,PRO-NHET9)-LUTEINIZINGHORMONE-RELEASINGFACTOR;[DES-GLY10,D-LEU6,PRO-NHET9]-LH-RH(HUMAN)

Pharmacological Effect

Leuprolide, goserelin, triprelin, and nafarelin are several drugs commonly used in clinical practice to remove ovaries for the treatment of premenopausal breast cancer and prostate cancer. (referred to as GnRH-a drugs), GnRH-a drugs are similar in structure to GnRH and compete with pituitary GnRH receptors. That is, the gonadotropin secreted by the pituitary decreases, which leads to a significant decrease in the sex hormone secreted by the ovary.

Leuprolide is a gonadotropin-releasing hormone (GnRH) analog, a peptide composed of 9 amino acids. This product can effectively inhibit the function of the pituitary-gonadal system, the resistance to proteolytic enzymes and the affinity to the pituitary GnRH receptor are stronger than GnRH, and the activity of promoting the release of luteinizing hormone (LH) is about 20 times that of GnRH. It also has a stronger inhibitory effect on pituitary-gonad function than GnRH. In the initial stage of treatment, follicle stimulating hormone (FSH), LH, estrogen or androgen may be temporarily increased, and then, due to the decreased responsiveness of the pituitary gland, the secretion of FSH, LH and estrogen or androgen is inhibited, resulting in dependence on sex hormones. Sexual diseases (such as prostate cancer, endometriosis, etc.) have a therapeutic effect.

At present, the acetate salt of leuprolide is mainly used clinically, because the performance of leuprolide acetate is more stable at room temperature. Liquid should be discarded. It can be used for the drug castration treatment of endometriosis and uterine fibroids, central precocious puberty, premenopausal breast cancer and prostate cancer, and also for functional uterine bleeding that is contraindicated or ineffective for conventional hormone therapy. It can also be used as a premedication before endometrial resection, which can evenly thin the endometrium, reduce edema, and reduce the difficulty of surgery.


Product detail pictures:

Wholesale Vancomycin And Tobramycin - Leuprorelin Acetate Regulates Secretion of Gonadal Hormones – Gentolex detail pictures

Wholesale Vancomycin And Tobramycin - Leuprorelin Acetate Regulates Secretion of Gonadal Hormones – Gentolex detail pictures


Related Product Guide:

To create more benefit for buyers is our business philosophy; shopper growing is our working chase for Wholesale Vancomycin And Tobramycin - Leuprorelin Acetate Regulates Secretion of Gonadal Hormones – Gentolex , The product will supply to all over the world, such as: Greece, Slovak Republic, Suriname, We insist on the principle of "Credit being primary, Customers being the king and Quality being the best", we are looking forward to the mutual cooperation with all friends at home and abroad and we will create a bright future of business.
  • The company leader recept us warmly, through a meticulous and thorough discussion, we signed a purchase order. Hope to cooperate smoothly
    5 Stars By Jack from Saudi Arabia - 2018.06.19 10:42
    Adhering to the business principle of mutual benefits, we have a happy and successful transaction, we think we will be the best business partner.
    5 Stars By Lulu from Zambia - 2018.06.26 19:27
    Write your message here and send it to us